公海赌赌船下载|Home

  • English
  • 旧版回顾
  • 教职工
  • 学校主页
  • 加入收藏

师资队伍

陈军
发布时间:2020/12/01   阅读量:

5e7ce73326efb3854815d92c871b63f.jpg

陈军

个人简介

博士,实验师,药学实验中心主任。2002年至公海赌赌船下载工作,期间参与重大专项“重大新药创制”两项,国家自然科学基金面上项目等其他纵向课题5项;2008年湖南省自然科学优秀学术论文二等奖,2012年湖南省优秀硕士论文奖,先后在国内外重要学术期刊发表论文10余篇,获发明专利授权3项。主要研究领域为合成药物化学:抗纤维化药物和抗糖尿病肾病药物的设计与合成,发明的抗糖尿病肾病药物美氟尼酮,目前正开展临床一期研究。

代表性文章

1. Jun Chen,Gaoyun Hu,Zhuo Chen,Xiaomin Wan,Chongqing Tan,Xiaohui Zeng,Zeneng Cheng,Cost-Effectiveness Analysis ofPembrolizumab plus Axitinibversus Sunitinib in First-Line Advanced Renal Cell Carcinoma in China,Clinical Drug Investigation 2019,39,931-938

2. Qunye He*, Jun Chen*, Jianhua Yan, Shundong Cai,Hongjie Xiong, Yanfei Liu, Dongming Peng, Miao Mo , ∗ , Zhenbao Liu,Tumor microenvironment responsive drug delivery systems,Asian Journal of Pharmaceutical Sciences 15 (2020) 416–448.

3. Jun Chen, Zhangzhe Peng, Miaomiao Lu, Xuan Xiong, Zhuo Chen, Qianbin Li, Zeneng Cheng, Dejian Jiang, Lijian Tao, Gaoyun Hu*. Discovery of 1-(4-((3-(4-methylpiperazin-1-yl)propyl)amino)benzyl)-5-(trifluoromethyl)pyridin- 2(1H)-one, an orally active multi-target agent for the treatment of diabetic nephropathy. Bioorg. Med.Chem. Lett., 2018, 28(2): 222-229.

4. Jun Chen, Miao-Miao Lu, Bin Liu, Zhuo Chen, Qian-Bin Li, Li-Jian Tao, Gao-Yun Hu*, Synthesis and structure–activity relationship of 5-substituent-2(1H)-pyridone derivatives as anti-fibrosis agents Bioorganic & Medicinal Chemistry Letters 2012, 22, 2300–2302

5. Ling Wu , Bin Liu , Qianbin Li , Jun Chen , Lijian Tao and Gaoyun Hu* , Design, Synthesis and Anti-fibrosis Activity Study of N1-Substituted Phenylhydroquinolinone Derivatives Molecules2012,17, 1373-1387

6.Chun Wu, Yanpeng Hu, Qianbin Li, Limei He, Jun Chen, Zeneng Cheng, Yuanjian Li,and Gaoyun Hu*, Synthesis, Pharmacokinetics, and Pharmacodynamics Studies of Valsartan Peptide Derivatives Arch. Pharm. Chem. Life Sci.2012, 345, 393–400

7. Zhuo Chen , Gaoyun Hu,*, Dai Li , Jun Chen , Yuanjian Li , Huayong Zhou , Ye Xie, Synthesis and vasodilator effects of rutaecarpine analogues which might be involved transient receptor potential vanilloid subfamily, member 1 (TRPV1) Bioorganic & Medicinal Chemistry2009, 17 , 2351–2359

8. Hua Yang, Gao-Yun Hu,* Jun Chen, Yi Wang and Zhong-Hua Wang, Synthesis, resolution, and antiplatelet activity of 3-substituted 1(3H)-isobenzofuranone Bioorganic & Medicinal Chemistry Letters 2007, 17 , 5210–5213

9.陈军,胡高云*,杨华,注射用头孢西丁钠有关物质测定方法的改进,中南药学,2007,5(2),121-123.

授权发明专利

(1)胡高云,陶立坚,陈军,1-(取代苄基)-5-三氟甲基-2-(1H)吡啶酮化合物及其盐的制备方法及其用途,2013.10.02,中国,ZL201080002577.6;2015.09.18,中国香港, HK1166791;2013.02.19,美国, US8377932;2015.2.25,欧洲, EP2474533;2015.04.03,日本, JP5722883;2014.12.24,韩国,KR101478133;2014.04.03,澳大利亚, AU2010252451.

(2)胡高云,陶立坚,陈军,1-(取代芳基)-5-三氟甲基-2-(1H)吡啶酮化合物及其盐的制备方法及其用途, 2012.12.05,中国,ZL201080002558.3;2014.08.08,中国香港, HK1164297;2013.04.23,美国, US8426407;2014.04.16,欧洲, EP2436670;2014.07.25,日本, JP5583758;2015.05.19,韩国, KR101522924;2014.08.28,澳大利亚, AU2010252447.

电话: (731) 82650440

传真: (731) 82650442

电子邮箱:yxychenjun@csu.edu.cn

上一条:董界

下一条:周文虎教授